Structured Summary
Abstract
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
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Synonyms
43 entry terms
- Polyendocrinopathies, Autoimmune
- Autoimmune Polyendocrinopathy
- Polyendocrinopathy, Autoimmune
- AIRE Deficiency
- APECED
- APS Type 1
- Autoimmune Polyendocrine Syndrome, Type 2
- Autoimmune Polyendocrine Syndrome, Type II
- Autoimmune Polyendocrinopathy Syndrome Type 1
- Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
- Autoimmune Polyglandular Syndrome Type I
- Autoimmune Polyglandular Syndrome Type II
- Autoimmune Polyglandular Syndrome Type III
- Autoimmune Polyglandular Syndrome, Type 1
- Autoimmune Polyglandular Syndrome, Type 3
- Autoimmune Polyglandular Syndrome, Type I
- Autoimmune Syndrome Type I, Polyglandular
- Autoimmune Syndrome Type II, Polyglandular
- Autoimmune Syndrome Type III, Polyglandular
- Diabetes Mellitus, Addison Disease, Myxedema
- Diabetes Mellitus, Addison's Disease, Myxedema
- Multiple Endocrine Deficiency Syndrome, Type 2
- Polyendocrine Autoimmune Syndrome, Type II
- Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
- Polyglandular Autoimmune Syndrome, Type 1
- Polyglandular Autoimmune Syndrome, Type 2
- Polyglandular Autoimmune Syndrome, Type 3
- Polyglandular Autoimmune Syndrome, Type I
- Polyglandular Deficiency Syndrome, Type 2
- Polyglandular Type I Autoimmune Syndrome
- Polyglandular Type II Autoimmune Syndrome
- Polyglandular Type III Autoimmune Syndrome
- Schmidt Syndrome
- Schmidt's Syndrome
- AIRE Deficiencies
- Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy
- Deficiency, AIRE
- Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune
- Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy, Autoimmune
- Syndrome, Schmidt
- Syndrome, Schmidt's
MeSH Record
Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
Indexing Annotation
do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed
MeSH Record
History Note
1992
MeSH Record
Previous Indexing
- Autoimmune Diseases (1968-1991)
- Endocrine Diseases (1978-1991)
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NLM Classification
WK 140
AMA Style
References
- National Library of Medicine. Autoimmune Polyendocrinopathies. Medical Subject Headings (MeSH). 2026. Unique ID D016884. http://id.nlm.nih.gov/mesh/2026/D016884
- Autoimmune Polyendocrinopathies. In: Wikipedia. https://en.wikipedia.org/wiki/Autoimmune_polyendocrine_syndrome
- Autoimmune Polyendocrinopathies. In: Wikidata. https://www.wikidata.org/wiki/Q675311