Diseases

Axial Spondyloarthritis

A spectrum of chronic inflammatory conditions affecting the axial joints (e.g., SPINE), characterized by pain, stiffness of joints (ANKYLOSIS), reduced mobility and inflammation. When joint inflammation and damage are visible on regular X-rays it is called ANKYLOSING SPONDYLITIS; otherwise it is referred to as NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS. HLA-B27 ANTIGEN is a biomarker and IL-23/IL-17 pathway a potential therapeutic target for axial and other related spondyloarthritis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A spectrum of chronic inflammatory conditions affecting the axial joints (e.g., SPINE), characterized by pain, stiffness of joints (ANKYLOSIS), reduced mobility and inflammation. When joint inflammation and damage are visible on regular X-rays it is called ANKYLOSING SPONDYLITIS; otherwise it is referred to as NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS. HLA-B27 ANTIGEN is a biomarker and IL-23/IL-17 pathway a potential therapeutic target for axial and other related spondyloarthritis.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • AxSpA
  • Axial Spondyloarthritides
  • Spondyloarthritides, Axial
  • Spondyloarthritis, Axial

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2022

MeSH Record

Previous Indexing

  • Spondylitis, Ankylosing (2006-2021)

MeSH Hierarchy

Tree Numbers

  1. C05w.116w.900w.853w.625.800w.744w
  2. C05w.550w.069w.340w
  3. C05w.550w.114w.865.800w.744w

AMA Style

References

  1. National Library of Medicine. Axial Spondyloarthritis. Medical Subject Headings (MeSH). 2026. Unique ID D000089183. http://id.nlm.nih.gov/mesh/2026/D000089183
  2. Axial Spondyloarthritis. In: Wikipedia. https://en.wikipedia.org/wiki/Axial_spondyloarthritis
  3. Axial Spondyloarthritis. In: Wikidata. https://www.wikidata.org/wiki/Q28867094