Structured Summary
Abstract
A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.
Chemical Identity
Chemical Information
- Molecular Formula
- C8H11N3O6
- Molecular Weight
- 245.19 g/mol
- CAS Registry No.
- 54-25-1
- IUPAC Name
- 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione
- InChIKey
- WYXSYVWAUAUWLD-SHUUEZRQSA-N
- SMILES
- C1=NN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- MeSH Unique ID
- D001380
- Source
- PubChem CID 5901
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
- 6-Azauridine
- 6 Azauridine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
73(72)
MeSH Record
Previous Indexing
- Antimetabolites (1966-1971)
- Uridine (1966-1971)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Azauridine. Medical Subject Headings (MeSH). 2026. Unique ID D001380. http://id.nlm.nih.gov/mesh/2026/D001380
- Azauridine. In: Wikidata. https://www.wikidata.org/wiki/Q27116561
- Azauridine. In: PubChem Compound. CID 5901. https://pubchem.ncbi.nlm.nih.gov/compound/5901