Structured Summary
Abstract
A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
See Also
MeSH Record
Synonyms
7 entry terms
- BRCA2 Gene Product
- Breast Cancer 2 Gene Product
- Breast Cancer 2 Protein
- FANCD1 Protein
- Fanconi Anemia Complementation Group D1 Protein
- Fanconi Anemia Group D1 Complementing Protein
- Fanconi Anemia Group D1 Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2002; use BRCA2 PROTEIN (NM) 1995-2001
MeSH Record
Previous Indexing
- Neoplasm Proteins (1995-2001)
- Transcription Factors (1995-2001)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. BRCA2 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D024682. http://id.nlm.nih.gov/mesh/2026/D024682
- BRCA2 Protein. In: Wikipedia. https://en.wikipedia.org/wiki/BRCA2
- BRCA2 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q421651