Structured Summary
Abstract
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
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Classification
Broader headings
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Synonyms
13 entry terms
- Basement Membranes
- Membrane, Basement
- Membranes, Basement
- Basal Lamina
- Basement Lamina
- Lamina Densa
- Lamina Lucida
- Lamina Reticularis
- Densas, Lamina
- Lamina, Basal
- Lamina, Basement
- Lucida, Lamina
- Reticularis, Lamina
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings abnormalities, anatomy & histology, blood supply, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, innervation, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, transplantation, ultrastructure, virology.
MeSH Record
Indexing Annotation
do not confuse entry term BASAL LAMINA with "lamina basalis", the basal plate of the embryonic neural tube
MeSH Record
History Note
67(65)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QS 532.5.E7
AMA Style
References
- National Library of Medicine. Basement Membrane. Medical Subject Headings (MeSH). 2026. Unique ID D001485. http://id.nlm.nih.gov/mesh/2026/D001485
- Basement Membrane. In: Wikipedia. https://en.wikipedia.org/wiki/Basement_membrane
- Basement Membrane. In: Wikidata. https://www.wikidata.org/wiki/Q32846