Chemicals and Drugs

Benzethonium

Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. The compound is toxic orally as a result of neuromuscular blockade.

Chemical Identity

Chemical Information

Molecular Formula
C27H42NO2+
Molecular Weight
412.6 g/mol
CAS Registry No.
10172-60-8
IUPAC Name
benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium
InChIKey
SIYLLGKDQZGJHK-UHFFFAOYSA-N
SMILES
CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCOCC[N+](C)(C)CC2=CC=CC=C2
MeSH Unique ID
D001558
Source
PubChem CID 2335

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • Bencetonium Chloride
  • Benzethonium Chloride
  • Formula Magic
  • Hyamine 1622
  • Orchid Fresh II
  • Phemeride
  • Phemerol
  • Phemethryn
  • Puri-Clens
  • Quatrachlor
  • Solamin
  • Chloride, Bencetonium
  • Chloride, Benzethonium
  • Magic, Formula
  • Puri Clens
  • PuriClens

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

91(81); was see under AMMONIUM COMPOUNDS 1981-90; was BENZETHONIUM CHLORIDE see under AMMONIUM COMPOUNDS 1975-80

MeSH Record

Previous Indexing

  • Ammonium Compounds (1969-1974)
  • Benzyl Compounds (1971-1974)
  • Phenyl Ethers (1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.877.096.082
  2. D02w.675w.276.090

AMA Style

References

  1. National Library of Medicine. Benzethonium. Medical Subject Headings (MeSH). 2026. Unique ID D001558. http://id.nlm.nih.gov/mesh/2026/D001558
  2. Benzethonium. In: Wikidata. https://www.wikidata.org/wiki/Q27166518
  3. Benzethonium. In: PubChem Compound. CID 2335. https://pubchem.ncbi.nlm.nih.gov/compound/2335