Structured Summary
Abstract
A rexinoid (an RXR-binding ligand), tetrahydronaphthalene derivative and RETINOID X RECEPTOR antagonist that is used in the treatment of CUTANEOUS T-CELL LYMPHOMA.
Chemical Identity
Chemical Information
- Molecular Formula
- C24H28O2
- Molecular Weight
- 348.5 g/mol
- CAS Registry No.
- 153559-49-0
- IUPAC Name
- 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid
- InChIKey
- NAVMQTYZDKMPEU-UHFFFAOYSA-N
- SMILES
- CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
- MeSH Unique ID
- D000077610
- Source
- PubChem CID 82146
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- 3-methyl-TTNEB
- 4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid
- LG69 compound
- LGD 1069
- LGD-1069
- LGD1069
- Targretin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1995)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Bexarotene. Medical Subject Headings (MeSH). 2026. Unique ID D000077610. http://id.nlm.nih.gov/mesh/2026/D000077610
- Bexarotene. In: Wikipedia. https://en.wikipedia.org/wiki/Bexarotene
- Bexarotene. In: Wikidata. https://www.wikidata.org/wiki/Q418192
- Bexarotene. In: PubChem Compound. CID 82146. https://pubchem.ncbi.nlm.nih.gov/compound/82146