Structured Summary
Abstract
Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
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Broader headings
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Drug Class
Pharmacological Action
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Synonyms
3 entry terms
- Antibodies, Blocking
- Antibodies, Enhancing
- Enhancing Antibodies
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen ( = ANTIBODIES or specific antibody); do not coordinate with ANTIBODY FORMATION for /biosyn
MeSH Record
History Note
96
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AMA Style
References
- National Library of Medicine. Blocking Antibodies. Medical Subject Headings (MeSH). 2026. Unique ID D019138. http://id.nlm.nih.gov/mesh/2026/D019138
- Blocking Antibodies. In: Wikipedia. https://en.wikipedia.org/wiki/Blocking_antibody
- Blocking Antibodies. In: Wikidata. https://www.wikidata.org/wiki/Q4927287