Anatomy

Blood-Testis Barrier

A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.

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Synonyms

9 entry terms
  • Testis-Blood Barrier
  • Barrier, Blood-Testis
  • Barrier, Testis-Blood
  • Barriers, Blood-Testis
  • Barriers, Testis-Blood
  • Blood Testis Barrier
  • Blood-Testis Barriers
  • Testis Blood Barrier
  • Testis-Blood Barriers

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings abnormalities, anatomy & histology, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, innervation, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, transplantation, ultrastructure, virology.

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Indexing Annotation

coord IM with endogenous substance /metab (IM) or exogenous substance /pharmacokin (IM)

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History Note

76(75); was see under TESTIS 1975

MeSH Record

Previous Indexing

  • Testis (1966-1974)

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Tree Numbers

AMA Style

References

  1. National Library of Medicine. Blood-Testis Barrier. Medical Subject Headings (MeSH). 2026. Unique ID D001814. http://id.nlm.nih.gov/mesh/2026/D001814
  2. Blood-Testis Barrier. In: Wikipedia. https://en.wikipedia.org/wiki/Blood%E2%80%93testis_barrier
  3. Blood-Testis Barrier. In: Wikidata. https://www.wikidata.org/wiki/Q489842