Chemicals and Drugs

Bongkrekic Acid

An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.

Chemical Identity

Chemical Information

Molecular Formula
C28H38O7
Molecular Weight
486.6 g/mol
CAS Registry No.
11076-19-0
IUPAC Name
(2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid
InChIKey
SHCXABJSXUACKU-WUTQZGRKSA-N
SMILES
C[C@@H](C/C=C/CC/C=C/C=C\C[C@H](/C(=C\C=C(/C)\C(=O)O)/C)OC)/C=C/C(=C\C(=O)O)/CC(=O)O
MeSH Unique ID
D001865
Source
PubChem CID 6433556

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Flavotoxin A
  • Bongkrekate

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under ANTIBIOTICS 1975-90

MeSH Record

Previous Indexing

  • Antibiotics (1973-1974)
  • Carboxylic Acids (1973-1974)
  • Pseudomonas (1968-1974)

MeSH Hierarchy

Tree Number

  1. D02w.241w.081.337w.075w

AMA Style

References

  1. National Library of Medicine. Bongkrekic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D001865. http://id.nlm.nih.gov/mesh/2026/D001865
  2. Bongkrekic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Bongkrek_acid
  3. Bongkrekic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q4941885
  4. Bongkrekic Acid. In: PubChem Compound. CID 6433556. https://pubchem.ncbi.nlm.nih.gov/compound/6433556