Chemicals and Drugs

C-Type Natriuretic Peptide

A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • C-Type Natriuretic Peptide-22
  • CNP-22
  • Natriuretic Peptide, C-Type
  • C Type Natriuretic Peptide
  • C Type Natriuretic Peptide 22
  • Natriuretic Peptide, C Type
  • Natriuretic Peptide-22, C-Type
  • Peptide, C-Type Natriuretic
  • Peptide-22, C-Type Natriuretic
  • C-Type Natriuretic Peptide-53
  • CNP-53
  • C Type Natriuretic Peptide 53
  • Natriuretic Peptide-53, C-Type
  • Peptide-53, C-Type Natriuretic

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1999; use C-TYPE NATRIURETIC PEPTIDE (NM) 1990-1998

MeSH Record

Previous Indexing

  • Nerve Tissue Proteins (1990-1994)
  • Proteins (1995-1998)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. C-Type Natriuretic Peptide. Medical Subject Headings (MeSH). 2026. Unique ID D020098. http://id.nlm.nih.gov/mesh/2026/D020098
  2. C-Type Natriuretic Peptide. In: Wikidata. https://www.wikidata.org/wiki/Q24745424