Chemicals and Drugs

CA-19-9 Antigen

Sialylated Lewis(a) blood group carbohydrate antigen found in many adenocarcinomas of the digestive tract, especially pancreatic tumors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Sialylated Lewis(a) blood group carbohydrate antigen found in many adenocarcinomas of the digestive tract, especially pancreatic tumors.

Chemical Identity

Chemical Information

Molecular Formula
C31H52N2O23
Molecular Weight
820.7 g/mol
IUPAC Name
(2S,4S,5R,6R)-5-acetamido-2-[(2R,3R,4S,5S,6R)-2-[(3R,4R,5S,6R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-4-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
InChIKey
XBSNXOHQOTUENA-KRAHZTDDSA-N
SMILES
C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H](OC([C@@H]([C@H]2O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O[C@@]4(C[C@@H]([C@H]([C@@H](O4)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)NC(=O)C)O)CO)O)O)O
MeSH Unique ID
D018395
Source
PubChem CID 10985677

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

21 entry terms
  • 5-Acetylneuraminyl-2-3-Galactosyl-1-3-(Fucopyranosyl-1-4)-N-Acetylglucosamine
  • Antigen CA-19-9
  • CA 19-9 Antigen
  • CA 19.9 Antigen
  • Gastrointestinal Cancer Antigen
  • NAG-1,3-F-1,4-GN
  • Neu5Ac-2-3-Gal-1-3-(Fuc-1-4)-GlcNAc
  • Sialyl Le(a)
  • Sialyl Lewis A
  • Sialyl Lewis A Antigen
  • Sialyl Lewis(a) Tetrasaccharide
  • alpha-Neu5Ac-(2-3)-beta-D-Gal-(1-3)-(alpha-L-Fuc-(1-4))-beta-D-GlcNAc
  • A, Sialyl Lewis
  • Antigen CA 19 9
  • Antigen, CA 19-9
  • Antigen, CA 19.9
  • Antigen, CA-19-9
  • CA 19 9 Antigen
  • CA-19-9, Antigen
  • Cancer Antigen, Gastrointestinal
  • Lewis A, Sialyl

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1995; was see ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE 1989-1994; for Sialyl Lewis A use OLIGOSACCHARIDES 1994-2019

MeSH Record

Previous Indexing

  • Antigens, Neoplasm (1984-1988)
  • Antigens, Tumor-Associated, Carbohydrate (1989-1994)

MeSH Hierarchy

Tree Numbers

  1. D23.050w.285.050.119w
  2. D23.050w.301.290.544w.119w
  3. D23.050w.550w.325.119w
  4. D23.050w.705.230.544w.119w
  5. D23.101w.140.075.119w

AMA Style

References

  1. National Library of Medicine. CA-19-9 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D018395. http://id.nlm.nih.gov/mesh/2026/D018395
  2. CA-19-9 Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/CA19-9
  3. CA-19-9 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q182517
  4. CA-19-9 Antigen. In: PubChem Compound. CID 10985677. https://pubchem.ncbi.nlm.nih.gov/compound/10985677