Chemicals and Drugs

CCAAT-Enhancer-Binding Proteins

A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.

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Classification

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Synonyms

20 entry terms
  • C-EBP Nuclear Protein
  • C-EBP Protein
  • C-EBP Proteins
  • CAAT-Enhancer Binding Protein
  • CAAT-Enhancer-Binding Proteins
  • CCAAT Sequence-Specific DNA-Binding Proteins
  • CCAAT-Enhancer-Binding Protein
  • Nuclear Protein C-EBP
  • Binding Protein, CAAT-Enhancer
  • C EBP Nuclear Protein
  • C EBP Protein
  • C EBP Proteins
  • C-EBP, Nuclear Protein
  • CAAT Enhancer Binding Protein
  • CAAT Enhancer Binding Proteins
  • CCAAT Enhancer Binding Protein
  • CCAAT Enhancer Binding Proteins
  • CCAAT Sequence Specific DNA Binding Proteins
  • Nuclear Protein C EBP
  • Nuclear Protein, C-EBP

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2001; for C-EBP NUCLEAR PROTEIN use CCAAT-ENHANCER-BINDING PROTEINS (NM) 1989-2000; for CCAAT SEQUENCE-SPECIFIC DNA-BINDING PROTEINS use CCAAT-ENHANCER BINDING PROTEINS 1988-2000

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1991-2000)
  • Nuclear Proteins (1991-2000)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. CCAAT-Enhancer-Binding Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D022762. http://id.nlm.nih.gov/mesh/2026/D022762
  2. CCAAT-Enhancer-Binding Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/CCAAT-enhancer-binding_proteins
  3. CCAAT-Enhancer-Binding Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q907967