Chemicals and Drugs

CD59 Antigens

Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Antigens, CD59
  • CD59 Antigen
  • HRF20
  • Homologous Restriction Factor 20
  • MACIF
  • Membrane Attack Complex Inhibition Factor
  • Membrane Inhibitor of Reactive Lysis
  • Protectin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1990); for PROTECTIN use CATIONIC PROTEIN, URATE-CALCIUM OXALATE STONE 1996-1999

MeSH Record

Previous Indexing

  • Antigens, CD (1990-1995)
  • Antigens, Differentiation (1989-1991)
  • Membrane Glycoproteins (1989-1995)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.448.140
  2. D12.776w.395w.550w.448.140
  3. D12.776w.543w.484w.500.140
  4. D12.776w.543w.550w.418.140

AMA Style

References

  1. National Library of Medicine. CD59 Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D018957. http://id.nlm.nih.gov/mesh/2026/D018957
  2. CD59 Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q24770793