Chemicals and Drugs

CRISPR-Associated Proteins

Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.

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Synonyms

12 entry terms
  • CRISPR Associated Proteins
  • Proteins, CRISPR-Associated
  • CASCADE Proteins, CRISPR-Associated
  • CRISPR-Associated Complex for Antiviral Defense Proteins
  • CRISPR-Associated Protein Complex Proteins
  • Repeat-Associated Mysterious Proteins
  • CASCADE Proteins, CRISPR Associated
  • CRISPR Associated Complex for Antiviral Defense Proteins
  • CRISPR Associated Protein Complex Proteins
  • CRISPR-Associated CASCADE Proteins
  • Proteins, Repeat-Associated Mysterious
  • Repeat Associated Mysterious Proteins

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Number

  1. D12.776w.212

AMA Style

References

  1. National Library of Medicine. CRISPR-Associated Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D064130. http://id.nlm.nih.gov/mesh/2026/D064130
  2. CRISPR-Associated Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78112144