Structured Summary
Abstract
A zinc finger motif of approximately 30 amino acids with the general sequence X2-Cys-X2,4-Cys-X12-His-X3,4,5-His that forms a simple beta sheet-beta sheet-alpha helix fold stabilized by zinc ions. It recognizes and binds to a variety of eukaryotic DNA sequences and is very common among sequence-specific DNA BINDING PROTEINS and TRANSCRIPTION FACTORS.
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Synonyms
20 entry terms
- C2H2 Zinc Fingers
- CYS2-HIS2 Zinc Finger Motifs
- CYS2HIS2 Zinc Fingers
- C2H2 Zinc Finger
- CYS2 HIS2 Zinc Finger Motifs
- CYS2 HIS2 Zinc Fingers
- CYS2-HIS2 Zinc Finger
- CYS2HIS2 Zinc Finger
- Finger, C2H2 Zinc
- Finger, CYS2-HIS2 Zinc
- Finger, CYS2HIS2 Zinc
- Fingers, C2H2 Zinc
- Fingers, CYS2-HIS2 Zinc
- Fingers, CYS2HIS2 Zinc
- Zinc Finger, C2H2
- Zinc Finger, CYS2-HIS2
- Zinc Finger, CYS2HIS2
- Zinc Fingers, C2H2
- Zinc Fingers, CYS2-HIS2
- Zinc Fingers, CYS2HIS2
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Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
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History Note
2017
MeSH Record
Previous Indexing
- Amino Acid Sequence (1990-2016)
- Zinc Fingers (1991-2016)
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AMA Style
References
- National Library of Medicine. CYS2-HIS2 Zinc Fingers. Medical Subject Headings (MeSH). 2026. Unique ID D000070580. http://id.nlm.nih.gov/mesh/2026/D000070580
- CYS2-HIS2 Zinc Fingers. In: Wikidata. https://www.wikidata.org/wiki/Q71236780