Chemicals and Drugs

Cabergoline

An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.

Chemical Identity

Chemical Information

Molecular Formula
C26H37N5O2
Molecular Weight
451.6 g/mol
CAS Registry No.
81409-90-7
IUPAC Name
(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
InChIKey
KORNTPPJEAJQIU-KJXAQDMKSA-N
SMILES
CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C
MeSH Unique ID
D000077465
Source
PubChem CID 54746

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
  • 1-Ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate
  • Cabaser
  • Cabaseril
  • Cabergoline Diphosphate
  • Dostinex
  • FCE 21336
  • FCE-21336
  • Galastop

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1985)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.327.287.131w
  2. D03w.633.400.439.197w

AMA Style

References

  1. National Library of Medicine. Cabergoline. Medical Subject Headings (MeSH). 2026. Unique ID D000077465. http://id.nlm.nih.gov/mesh/2026/D000077465
  2. Cabergoline. In: Wikipedia. https://en.wikipedia.org/wiki/Cabergoline
  3. Cabergoline. In: Wikidata. https://www.wikidata.org/wiki/Q423308
  4. Cabergoline. In: PubChem Compound. CID 54746. https://pubchem.ncbi.nlm.nih.gov/compound/54746