Structured Summary
Abstract
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
17 entry terms
- 60B8-B Antigen
- CABP-P8
- Cystic Fibrosis Antigen
- Leukocyte L1 Protein Light Chain
- MRP-8 Protein
- MRP8 Protein
- Macrophage-Related Protein-8
- Myeloid Calcium-Binding Protein P8
- S100 A8 Protein
- S100A8 Protein
- 60B8 B Antigen
- A8 Protein, S100
- Antigen, 60B8-B
- Antigen, Cystic Fibrosis
- MRP 8 Protein
- Macrophage Related Protein 8
- Myeloid Calcium Binding Protein P8
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2003; use CALGRANULIN A (NM) 1998-2002;
MeSH Record
Previous Indexing
- Antigens, Differentiation (1989-2002)
- Calcium-Binding Proteins (1989-2002)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Calgranulin A. Medical Subject Headings (MeSH). 2026. Unique ID D040501. http://id.nlm.nih.gov/mesh/2026/D040501
- Calgranulin A. In: Wikidata. https://www.wikidata.org/wiki/Q21114543