Structured Summary
Abstract
A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
2 entry terms
- Calponin
- Calponin Family Proteins
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2024
MeSH Record
Previous Indexing
- Microfilament Proteins (1990-2023)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Calponins. Medical Subject Headings (MeSH). 2026. Unique ID D000096985. http://id.nlm.nih.gov/mesh/2026/D000096985
- Calponins. In: Wikipedia. https://en.wikipedia.org/wiki/Calponin
- Calponins. In: Wikidata. https://www.wikidata.org/wiki/Q24744812