Structured Summary
Abstract
An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice. It causes leukemia and thrombocytopenia in almost all human patients.
Chemical Identity
Chemical Information
- Molecular Formula
- C15H19N3O5
- Molecular Weight
- 321.33 g/mol
- CAS Registry No.
- 24279-91-2
- IUPAC Name
- [2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl] carbamate
- InChIKey
- SHHKQEUPHAENFK-UHFFFAOYSA-N
- SMILES
- CC1=C(C(=O)C(=C(C1=O)N2CC2)C(COC(=O)N)OC)N3CC3
- MeSH Unique ID
- D002225
- Source
- PubChem CID 2569
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
3 entry terms
- Carboquinone
- Carboquone
- Esquinon
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under AZIRINES 1975-90
MeSH Record
Previous Indexing
- Azirines (1971-1974)
- Carbamates (1972-1974)
- Quinones (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Carbazilquinone. Medical Subject Headings (MeSH). 2026. Unique ID D002225. http://id.nlm.nih.gov/mesh/2026/D002225
- Carbazilquinone. In: Wikipedia. https://en.wikipedia.org/wiki/Carboquone
- Carbazilquinone. In: Wikidata. https://www.wikidata.org/wiki/Q5038065
- Carbazilquinone. In: PubChem Compound. CID 2569. https://pubchem.ncbi.nlm.nih.gov/compound/2569