Structured Summary
Abstract
An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H16N2O5
- Molecular Weight
- 244.24 g/mol
- CAS Registry No.
- 38821-49-7
- IUPAC Name
- (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid;hydrate
- InChIKey
- QTAOMKOIBXZKND-PPHPATTJSA-N
- SMILES
- C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O
- MeSH Unique ID
- D002230
- Source
- PubChem CID 38101
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
11 entry terms
- Methyldopahydrazine
- Carbidopa, (R)-Isomer
- Carbidopa, (S)-Isomer
- Lodosin
- Lodosyn
- MK-485
- MK-486
- MK 485
- MK 486
- MK485
- MK486
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79; was METHYLDOPAHYDRAZINE 1973-74 (Prov)
MeSH Record
Previous Indexing
- Dopa (1972-1974)
- Hydrazines (1972-1974)
- Methyldopa (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Carbidopa. Medical Subject Headings (MeSH). 2026. Unique ID D002230. http://id.nlm.nih.gov/mesh/2026/D002230
- Carbidopa. In: Wikidata. https://www.wikidata.org/wiki/Q414225
- Carbidopa. In: PubChem Compound. CID 38101. https://pubchem.ncbi.nlm.nih.gov/compound/38101