Chemicals and Drugs

Caspase 12

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Caspase-12

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(2000)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.262w.500.126w.550.920w
  2. D08.811w.277w.656w.300w.200.126w.550.920w
  3. D12.776w.476.075.405w.550.920w

AMA Style

References

  1. National Library of Medicine. Caspase 12. Medical Subject Headings (MeSH). 2026. Unique ID D053454. http://id.nlm.nih.gov/mesh/2026/D053454
  2. Caspase 12. In: Wikipedia. https://en.wikipedia.org/wiki/Caspase_12
  3. Caspase 12. In: Wikidata. https://www.wikidata.org/wiki/Q18068044