Structured Summary
Abstract
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
10 entry terms
- Caspase-2
- ICH-1 Protease
- ICH 1 Protease
- Caspase 2 Subunit p12
- Caspase 2 Subunit p13
- Caspase 2 Subunit p18
- Pro-Caspase-2
- Procaspase-2
- Pro Caspase 2
- Procaspase 2
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1994)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Caspase 2. Medical Subject Headings (MeSH). 2026. Unique ID D053143. http://id.nlm.nih.gov/mesh/2026/D053143
- Caspase 2. In: Wikidata. https://www.wikidata.org/wiki/Q32855884