Chemicals and Drugs

Cathepsin B

A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • Cathepsin B1
  • Cathepsin B-Like Proteinase
  • Cathepsin B Like Proteinase
  • Proteinase, Cathepsin B-Like

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Cathepsins (1966-1986)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cathepsin B. Medical Subject Headings (MeSH). 2026. Unique ID D002401. http://id.nlm.nih.gov/mesh/2026/D002401
  2. Cathepsin B. In: Wikidata. https://www.wikidata.org/wiki/Q4217285