Structured Summary
Abstract
Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.
Chemical Identity
Chemical Information
- Molecular Formula
- C18H18N6O5S2
- Molecular Weight
- 462.5 g/mol
- CAS Registry No.
- 34444-01-4
- IUPAC Name
- (6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- InChIKey
- OLVCFLKTBJRLHI-AXAPSJFSSA-N
- SMILES
- CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)[C@@H](C4=CC=CC=C4)O)SC2)C(=O)O
- MeSH Unique ID
- D002435
- Source
- PubChem CID 456255
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
2 entry terms
- Cephamandole
- Compound 83405
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
84(78); was see under CEPHALOSPORINS 1978-83
MeSH Record
Previous Indexing
- Cephalosporins (1966-1977)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QV 350.5.C3
AMA Style
References
- National Library of Medicine. Cefamandole. Medical Subject Headings (MeSH). 2026. Unique ID D002435. http://id.nlm.nih.gov/mesh/2026/D002435
- Cefamandole. In: Wikipedia. https://en.wikipedia.org/wiki/Cefamandole
- Cefamandole. In: Wikidata. https://www.wikidata.org/wiki/Q2601530
- Cefamandole. In: PubChem Compound. CID 456255. https://pubchem.ncbi.nlm.nih.gov/compound/456255