Chemicals and Drugs

Cefepime

A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fourth-generation cephalosporin antibacterial agent that is used in the treatment of infections, including those of the abdomen, urinary tract, respiratory tract, and skin. It is effective against PSEUDOMONAS AERUGINOSA and may also be used in the empiric treatment of FEBRILE NEUTROPENIA.

Chemical Identity

Chemical Information

Molecular Formula
C19H24N6O5S2
Molecular Weight
480.6 g/mol
CAS Registry No.
88040-23-7
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey
HVFLCNVBZFFHBT-ZKDACBOMSA-N
SMILES
C[N+]1(CCCC1)CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)[O-]
MeSH Unique ID
D000077723
Source
PubChem CID 5479537

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Cefepim
  • Axépim
  • BMY 28142
  • BMY-28142
  • Cefepime Hydrochloride
  • Maxipime
  • Quadrocef
  • BMY28142

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1985)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.173w
  2. D02w.886w.665w.074w.173w
  3. D03w.633.100.300w.249w.173w

AMA Style

References

  1. National Library of Medicine. Cefepime. Medical Subject Headings (MeSH). 2026. Unique ID D000077723. http://id.nlm.nih.gov/mesh/2026/D000077723
  2. Cefepime. In: Wikipedia. https://en.wikipedia.org/wiki/Cefepime
  3. Cefepime. In: Wikidata. https://www.wikidata.org/wiki/Q2552927
  4. Cefepime. In: PubChem Compound. CID 5479537. https://pubchem.ncbi.nlm.nih.gov/compound/5479537