Chemicals and Drugs

Cefmetazole

A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

Chemical Identity

Chemical Information

Molecular Formula
C15H17N7O5S3
Molecular Weight
471.5 g/mol
CAS Registry No.
56796-20-4
IUPAC Name
(6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
SNBUBQHDYVFSQF-HIFRSBDPSA-N
SMILES
CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)O
MeSH Unique ID
D015311
Source
PubChem CID 42008

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • CS-1170
  • Cefmetazole Monosodium Salt
  • Cefmetazole Sodium
  • Cefmetazon
  • U-72791A
  • Zefazone
  • CS 1170
  • CS1170
  • Monosodium Salt, Cefmetazole
  • Salt, Cefmetazole Monosodium
  • Sodium, Cefmetazole
  • U 72791A
  • U72791A

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Cephamycins (1979-1988)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.250w.177w
  2. D02w.886w.665w.074w.250w.177w
  3. D03w.633.100.300w.249w.250w.177w

AMA Style

References

  1. National Library of Medicine. Cefmetazole. Medical Subject Headings (MeSH). 2026. Unique ID D015311. http://id.nlm.nih.gov/mesh/2026/D015311
  2. Cefmetazole. In: Wikipedia. https://en.wikipedia.org/wiki/Cefmetazole
  3. Cefmetazole. In: Wikidata. https://www.wikidata.org/wiki/Q5057238
  4. Cefmetazole. In: PubChem Compound. CID 42008. https://pubchem.ncbi.nlm.nih.gov/compound/42008