Chemicals and Drugs

Cefonicid

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Chemical Identity

Chemical Information

Molecular Formula
C18H18N6O8S3
Molecular Weight
542.6 g/mol
CAS Registry No.
61270-58-4
IUPAC Name
(6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
DYAIAHUQIPBDIP-AXAPSJFSSA-N
SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)O)C(=O)O)CSC4=NN=NN4CS(=O)(=O)O
MeSH Unique ID
D015790
Source
PubChem CID 43594

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Cefonicid Disodium Salt
  • Cefonicid Monosodium
  • Cefonicid Monosodium Salt
  • Monocid
  • SK&F-75073
  • SKF-75073-2
  • Sodium Cefonicid
  • Cefonicid, Sodium
  • SK&F 75073
  • SK&F75073
  • SKF 75073 2
  • SKF750732

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Cefamandole/analogs & derivatives (1978-1989)
  • Cephalosporins (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.177w
  2. D02w.886w.665w.074w.177w
  3. D03w.633.100.300w.249w.177w

AMA Style

References

  1. National Library of Medicine. Cefonicid. Medical Subject Headings (MeSH). 2026. Unique ID D015790. http://id.nlm.nih.gov/mesh/2026/D015790
  2. Cefonicid. In: Wikipedia. https://en.wikipedia.org/wiki/Cefonicid
  3. Cefonicid. In: Wikidata. https://www.wikidata.org/wiki/Q5057286
  4. Cefonicid. In: PubChem Compound. CID 43594. https://pubchem.ncbi.nlm.nih.gov/compound/43594