Chemicals and Drugs

Cefozopran

A fourth-generation cephalosporin antibacterial agent with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Cefozopran has a 1-methyltetrazolethiol (MTT) moiety at C-3 of its cephalosporin core.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fourth-generation cephalosporin antibacterial agent with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Cefozopran has a 1-methyltetrazolethiol (MTT) moiety at C-3 of its cephalosporin core.

Chemical Identity

Chemical Information

Molecular Formula
C19H17N9O5S2
Molecular Weight
515.5 g/mol
CAS Registry No.
113359-04-9
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey
QDUIJCOKQCCXQY-WHJQOFBOSA-N
SMILES
CO/N=C(/C1=NSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=C5C=CC=NN5C=C4)C(=O)[O-]
MeSH Unique ID
D000097586
Source
PubChem CID 9571080

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Cefozopran (CZOP)
  • Cefozopran HCL
  • Cefozopran Hydrochloride
  • SCE 2787
  • SCE-2787
  • 2787, SCE
  • HCL, Cefozopran
  • Hydrochloride, Cefozopran
  • SCE2787

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2024 (1991)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.179w
  2. D02w.886w.665w.074w.179w
  3. D03w.383.129w.617.264w
  4. D03w.633.100.300w.249w.179w

AMA Style

References

  1. National Library of Medicine. Cefozopran. Medical Subject Headings (MeSH). 2026. Unique ID D000097586. http://id.nlm.nih.gov/mesh/2026/D000097586
  2. Cefozopran. In: Wikipedia. https://en.wikipedia.org/wiki/Cefozopran
  3. Cefozopran. In: Wikidata. https://www.wikidata.org/wiki/Q5057291
  4. Cefozopran. In: PubChem Compound. CID 9571080. https://pubchem.ncbi.nlm.nih.gov/compound/9571080