Chemicals and Drugs

Central Muscle Relaxants

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)

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Classification

Broader headings

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See Also

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Synonyms

3 entry terms
  • Centrally Acting Muscle Relaxants
  • Muscle Relaxants, Central
  • Relaxants, Central Muscle

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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Indexing Annotation

refers to skeletal muscle relaxants only: smooth muscle relaxants = PARASYMPATHOLYTICS

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History Note

70; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69

MeSH Record

Previous Indexing

  • Muscles (1966-1969)

MeSH Hierarchy

Tree Numbers

  1. D27.505.696.510
  2. D27.505.696.663.700.600
  3. D27.505.954.427.525

MeSH Record

NLM Classification

QV 140

AMA Style

References

  1. National Library of Medicine. Central Muscle Relaxants. Medical Subject Headings (MeSH). 2026. Unique ID D009125. http://id.nlm.nih.gov/mesh/2026/D009125
  2. Central Muscle Relaxants. In: Wikidata. https://www.wikidata.org/wiki/Q50430093