Chemicals and Drugs

Chemokine CX3CL1

A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.

MeSH Record

Classification

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MeSH Record

Synonyms

6 entry terms
  • CX3CL1 Chemokine
  • Chemokine (C-X3-C Motif) Ligand 1
  • Fractalkine
  • Neurotactin
  • CX3CL1, Chemokine
  • Chemokine, CX3CL1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Chemokine CX3CL1. Medical Subject Headings (MeSH). 2026. Unique ID D054428. http://id.nlm.nih.gov/mesh/2026/D054428
  2. Chemokine CX3CL1. In: Wikidata. https://www.wikidata.org/wiki/Q24784114