Chemicals and Drugs

Chemokine CXCL12

A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.

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Classification

Broader headings

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MeSH Record

Synonyms

20 entry terms
  • CXCL12 Chemokine
  • Chemokine (C-X-C Motif) Ligand 12
  • Pre-B-Cell Growth-Stimulating Factor
  • Stromal Cell-Derived Factor 1
  • CXCL12, Chemokine
  • Chemokine, CXCL12
  • Growth-Stimulating Factor, Pre-B-Cell
  • Pre B Cell Growth Stimulating Factor
  • Stromal Cell Derived Factor 1
  • SDF-1alpha
  • SDF-1beta
  • SDF1-3'A
  • Stromal Cell-Derived Factor-1alpha
  • Stromal Cell-Derived Factor-1beta
  • Cell-Derived Factor-1beta, Stromal
  • SDF 1alpha
  • SDF 1beta
  • SDF1 3'A
  • Stromal Cell Derived Factor 1alpha
  • Stromal Cell Derived Factor 1beta

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1993)

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AMA Style

References

  1. National Library of Medicine. Chemokine CXCL12. Medical Subject Headings (MeSH). 2026. Unique ID D054377. http://id.nlm.nih.gov/mesh/2026/D054377
  2. Chemokine CXCL12. In: Wikidata. https://www.wikidata.org/wiki/Q59251661