Chemicals and Drugs

Chloroquine

The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.

Chemical Identity

Chemical Information

Molecular Formula
C18H26ClN3
Molecular Weight
319.9 g/mol
CAS Registry No.
54-05-7
IUPAC Name
4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine
InChIKey
WHTVZRBIWZFKQO-UHFFFAOYSA-N
SMILES
CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
MeSH Unique ID
D002738
Source
PubChem CID 2719

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Chingamin
  • Chlorochin
  • Khingamin
  • Aralen
  • Arechine
  • Arequin
  • Chloroquine Sulfate
  • Chloroquine Sulphate
  • Nivaquine
  • Sulfate, Chloroquine
  • Sulphate, Chloroquine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 256

AMA Style

References

  1. National Library of Medicine. Chloroquine. Medical Subject Headings (MeSH). 2026. Unique ID D002738. http://id.nlm.nih.gov/mesh/2026/D002738
  2. Chloroquine. In: Wikipedia. https://en.wikipedia.org/wiki/Chloroquine
  3. Chloroquine. In: Wikidata. https://www.wikidata.org/wiki/Q422438
  4. Chloroquine. In: PubChem Compound. CID 2719. https://pubchem.ncbi.nlm.nih.gov/compound/2719