Structured Summary
Abstract
A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
Chemical Identity
Chemical Information
- Molecular Formula
- C14H11ClN2O4S
- Molecular Weight
- 338.8 g/mol
- CAS Registry No.
- 77-36-1
- IUPAC Name
- 2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
- InChIKey
- JIVPVXMEBJLZRO-UHFFFAOYSA-N
- SMILES
- C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
- MeSH Unique ID
- D002752
- Source
- PubChem CID 2732
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Chlorphthalidolone
- Chlortalidone
- Oxodoline
- Phthalamudine
- Hygroton
- Thalitone
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Chlorthalidone. Medical Subject Headings (MeSH). 2026. Unique ID D002752. http://id.nlm.nih.gov/mesh/2026/D002752
- Chlorthalidone. In: Wikipedia. https://en.wikipedia.org/wiki/Chlortalidone
- Chlorthalidone. In: Wikidata. https://www.wikidata.org/wiki/Q425289
- Chlorthalidone. In: PubChem Compound. CID 2732. https://pubchem.ncbi.nlm.nih.gov/compound/2732