Chemicals and Drugs

Cholestenone 5 alpha-Reductase

An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • 4-Ene Steroid 5 alpha-Reductase
  • 5 alpha-Reductase
  • 4 Ene Steroid 5 alpha Reductase
  • 5 alpha Reductase
  • 5 alpha-Reductase, Cholestenone
  • Cholestenone 5 alpha Reductase
  • alpha-Reductase, Cholestenone 5

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2004; use CHOLESTENONE 5 ALPHA-REDUCTASE (NM) 1980-2003

MeSH Record

Previous Indexing

  • Cholestenones (1970-1982)
  • Oxidoreductases (1983-2003)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Cholestenone 5 alpha-Reductase. Medical Subject Headings (MeSH). 2026. Unique ID D042944. http://id.nlm.nih.gov/mesh/2026/D042944
  2. Cholestenone 5 alpha-Reductase. In: Wikipedia. https://en.wikipedia.org/wiki/Cholestenone_5alpha-reductase
  3. Cholestenone 5 alpha-Reductase. In: Wikidata. https://www.wikidata.org/wiki/Q3133231