Chemicals and Drugs

Choline-Phosphate Cytidylyltransferase

An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

20 entry terms
  • CDP-Choline Synthetase
  • CTP Phosphocholine Cytidylyl-Transferase
  • CTP Phosphocholine Cytidylyltransferase
  • CTP Phosphorylcholine Cytidyltransferase
  • Phosphocholine Cytidyltransferase
  • Phosphorylcholine Cytidyl Transferase
  • CDP Choline Synthetase
  • CTP Phosphocholine Cytidylyl Transferase
  • Choline Phosphate Cytidylyltransferase
  • Cytidyl Transferase, Phosphorylcholine
  • Cytidyltransferase, CTP Phosphorylcholine
  • Cytidyltransferase, Phosphocholine
  • Cytidylyl-Transferase, CTP Phosphocholine
  • Cytidylyltransferase, CTP Phosphocholine
  • Cytidylyltransferase, Choline-Phosphate
  • Phosphocholine Cytidylyl-Transferase, CTP
  • Phosphocholine Cytidylyltransferase, CTP
  • Phosphorylcholine Cytidyltransferase, CTP
  • Synthetase, CDP-Choline
  • Transferase, Phosphorylcholine Cytidyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98; use CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE (NM) 1980-97

MeSH Record

Previous Indexing

  • Choline (1975-1977)
  • Cytidine Diphosphate Choline (1977-1981)
  • Cytosine Nucleotides (1975-1977)
  • Nucleotidyltransferases (1975-1997)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.696w.445w.184w

AMA Style

References

  1. National Library of Medicine. Choline-Phosphate Cytidylyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D019916. http://id.nlm.nih.gov/mesh/2026/D019916
  2. Choline-Phosphate Cytidylyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Choline-phosphate_cytidylyltransferase
  3. Choline-Phosphate Cytidylyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q5104336