Chemicals and Drugs

Chromogranin A

A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • CHGA Protein
  • Parathyroid Secretory Protein
  • Secretory Protein I, Parathyroid Gland
  • Secretory Protein, Parathyroid

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007 (1981)

MeSH Record

Previous Indexing

  • Adrenal Medulla (1968-2003)
  • Chromogranins (1973-2006)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Chromogranin A. Medical Subject Headings (MeSH). 2026. Unique ID D053379. http://id.nlm.nih.gov/mesh/2026/D053379
  2. Chromogranin A. In: Wikipedia. https://en.wikipedia.org/wiki/Chromogranin-A
  3. Chromogranin A. In: Wikidata. https://www.wikidata.org/wiki/Q3698322