Diseases

Chronic Idiopathic Jaundice

A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

12 entry terms
  • Dubin-Johnson Syndrome
  • Hyperbilirubinemia 2
  • Hyperbilirubinemia II
  • Jaundice, Chronic Idiopathic
  • Chronic Idiopathic Jaundices
  • Dubin Johnson Syndrome
  • Hyperbilirubinemia 2s
  • Hyperbilirubinemia IIs
  • Idiopathic Jaundice, Chronic
  • Idiopathic Jaundices, Chronic
  • Jaundices, Chronic Idiopathic
  • Syndrome, Dubin-Johnson

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Hierarchy

Tree Numbers

  1. C16w.320w.565w.300w.764w
  2. C16w.614.451.500w.250w
  3. C18.452w.648w.300w.764w
  4. C23.550.291.500w.479w

MeSH Record

NLM Classification

WI 703

AMA Style

References

  1. National Library of Medicine. Chronic Idiopathic Jaundice. Medical Subject Headings (MeSH). 2026. Unique ID D007566. http://id.nlm.nih.gov/mesh/2026/D007566
  2. Chronic Idiopathic Jaundice. In: Wikipedia. https://en.wikipedia.org/wiki/Dubin%E2%80%93Johnson_syndrome
  3. Chronic Idiopathic Jaundice. In: Wikidata. https://www.wikidata.org/wiki/Q1263039