Diseases

Cloacal Exstrophy

A rare congenital malformation that affects the development of the urinary, digestive, and REPRODUCTIVE SYSTEMS due to CLOACA malformations. In this condition, the large intestine develops outside the abdominal cavity, with the bladder connected to it. Due to this abnormal connection between the colon and the bladder, urine and stool can mix, and there is often no anus.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A rare congenital malformation that affects the development of the urinary, digestive, and REPRODUCTIVE SYSTEMS due to CLOACA malformations. In this condition, the large intestine develops outside the abdominal cavity, with the bladder connected to it. Due to this abnormal connection between the colon and the bladder, urine and stool can mix, and there is often no anus.

MeSH Record

Classification

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MeSH Record

Synonyms

16 entry terms
  • Cloacal Exstrophies
  • Exstrophies, Cloacal
  • Exstrophy, Cloacal
  • Congenital Vesico-intestinal Fissure
  • Congenital Vesicointestinal Fissure
  • Congenital Vesico intestinal Fissure
  • Congenital Vesico-intestinal Fissures
  • Congenital Vesicointestinal Fissures
  • Fissure, Congenital Vesico-intestinal
  • Fissure, Congenital Vesicointestinal
  • Fissures, Congenital Vesico-intestinal
  • Fissures, Congenital Vesicointestinal
  • Vesico-intestinal Fissure, Congenital
  • Vesico-intestinal Fissures, Congenital
  • Vesicointestinal Fissure, Congenital
  • Vesicointestinal Fissures, Congenital

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2025

MeSH Record

Previous Indexing

  • Bladder Exstrophy(1972-2024)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cloacal Exstrophy. Medical Subject Headings (MeSH). 2026. Unique ID D000099005. http://id.nlm.nih.gov/mesh/2026/D000099005
  2. Cloacal Exstrophy. In: Wikipedia. https://en.wikipedia.org/wiki/Cloacal_exstrophy
  3. Cloacal Exstrophy. In: Wikidata. https://www.wikidata.org/wiki/Q5134736