Phenomena and Processes

Codon Usage

The frequency of occurrence, in a specific organism's DNA sequence, of one of several potential synonymous codons that code for a particular amino acid. Frequently, there is a nonrandom pattern (bias) in the usage of a particular codon or codons over other synonymous codons.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The frequency of occurrence, in a specific organism's DNA sequence, of one of several potential synonymous codons that code for a particular amino acid. Frequently, there is a nonrandom pattern (bias) in the usage of a particular codon or codons over other synonymous codons.

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Classification

Broader headings

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MeSH Record

Synonyms

5 entry terms
  • Synonymous Codon Usage
  • Codon Bias
  • Codon Preference
  • Codon Usage Bias
  • Codon Usage Pattern

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Codon (1979-2019)

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AMA Style

References

  1. National Library of Medicine. Codon Usage. Medical Subject Headings (MeSH). 2026. Unique ID D000081183. http://id.nlm.nih.gov/mesh/2026/D000081183
  2. Codon Usage. In: Wikipedia. https://en.wikipedia.org/wiki/Codon_usage_bias
  3. Codon Usage. In: Wikidata. https://www.wikidata.org/wiki/Q1106472