Structured Summary
Abstract
A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a comet with tail formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
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Synonyms
19 entry terms
- Electrophoresis, Gel, Single-Cell
- Gel Electrophoresis, Single-Cell
- Assay, Comet
- Assays, Comet
- Comet Assays
- Electrophoreses, Single-Cell Gel
- Electrophoresis, Single-Cell Gel
- Gel Electrophoreses, Single-Cell
- Gel Electrophoresis, Single Cell
- Single-Cell Gel Electrophoreses
- Single-Cell Gel Electrophoresis
- Alkaline Comet Assay
- Alkaline Single-Cell Gel Electrophoresis Assay
- Alkaline Comet Assays
- Alkaline Single Cell Gel Electrophoresis Assay
- Assay, Alkaline Comet
- Assays, Alkaline Comet
- Comet Assay, Alkaline
- Comet Assays, Alkaline
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Aspects Covered
10 allowable subheadings
Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.
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History Note
2000
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Previous Indexing
- Electrophoresis (1990-1999)
- Electrophoresis, Agar Gel (1990-1999)
- Mutagenicity Tests (1992-1999)
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AMA Style
References
- National Library of Medicine. Comet Assay. Medical Subject Headings (MeSH). 2026. Unique ID D020552. http://id.nlm.nih.gov/mesh/2026/D020552
- Comet Assay. In: Wikipedia. https://en.wikipedia.org/wiki/Comet_assay
- Comet Assay. In: Wikidata. https://www.wikidata.org/wiki/Q903780