Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Compassionate Use Trials

Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

18 entry terms
  • Expanded Access Trials
  • Access Trial, Expanded
  • Compassionate Use Trial
  • Expanded Access Trial
  • Trial, Compassionate Use
  • Trial, Expanded Access
  • Trials, Compassionate Use
  • Trials, Expanded Access
  • Use Trials, Compassionate
  • Compassionate Use
  • Humanitarian Device Exemption
  • Compassionate Uses
  • Device Exemption, Humanitarian
  • Device Exemptions, Humanitarian
  • Exemption, Humanitarian Device
  • Exemptions, Humanitarian Device
  • Humanitarian Device Exemptions
  • Use, Compassionate

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, legislation & jurisprudence, methods, mortality, nursing, psychology, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

2010

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Compassionate Use Trials. Medical Subject Headings (MeSH). 2026. Unique ID D057176. http://id.nlm.nih.gov/mesh/2026/D057176
  2. Compassionate Use Trials. In: Wikipedia. https://en.wikipedia.org/wiki/Expanded_access
  3. Compassionate Use Trials. In: Wikidata. https://www.wikidata.org/wiki/Q407954