Structured Summary
Abstract
A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
MeSH Record
Classification
Broader headings
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- C2 Complement
- Complement 2
- Complement Component 2
- C2, Complement
- Complement, C2
- Component 2, Complement
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1975)
MeSH Record
Previous Indexing
- Complement (1968-1974)
- Magnesium (1966-1974)
- Protein Binding (1966-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C2. Medical Subject Headings (MeSH). 2026. Unique ID D003175. http://id.nlm.nih.gov/mesh/2026/D003175
- Complement C2. In: Wikidata. https://www.wikidata.org/wiki/Q43921640