Structured Summary
Abstract
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue.
MeSH Record
Classification
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
23 entry terms
- C3-C5 Convertase
- C3 C5 Convertase
- C3-C5 Convertases, Complement
- Complement C3 C5 Convertases
- Convertase, C3-C5
- Convertases, Complement C3-C5
- C 3 Convertase
- C3 Activator
- C3 Convertase
- C5 Cleaving Enzyme
- C5 Convertase
- Complement 3 Convertase
- Complement 5 Convertase
- Complement C3 Convertases
- Complement C5 Convertases
- Activator, C3
- C3 Convertases, Complement
- C5 Convertases, Complement
- Convertase, C 3
- Convertase, C3
- Convertase, Complement 3
- Convertases, Complement C3
- Convertases, Complement C5
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1978)
MeSH Record
Previous Indexing
- Complement C3 (1976-2005)
- Complement C5 (1976-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C3-C5 Convertases. Medical Subject Headings (MeSH). 2026. Unique ID D050577. http://id.nlm.nih.gov/mesh/2026/D050577
- Complement C3-C5 Convertases. In: Wikidata. https://www.wikidata.org/wiki/Q77452258