Chemicals and Drugs

Complement C3d

A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c, and C3dg (955-1303) in the presence COMPLEMENT FACTOR H. Serum proteases further degrade C3dg into C3d (1002-1303) and C3g (955-1001).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c, and C3dg (955-1303) in the presence COMPLEMENT FACTOR H. Serum proteases further degrade C3dg into C3d (1002-1303) and C3g (955-1001).

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Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

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See Also

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Synonyms

9 entry terms
  • C3d Complement
  • Complement 3d
  • Complement C3d Fragment
  • Complement Component 3d
  • C3d Fragment, Complement
  • C3d, Complement
  • Complement, C3d
  • Component 3d, Complement
  • Fragment, Complement C3d

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1990)

MeSH Record

Previous Indexing

  • Complement (1973-1976)
  • Complement 3 (1975-1989)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Complement C3d. Medical Subject Headings (MeSH). 2026. Unique ID D015933. http://id.nlm.nih.gov/mesh/2026/D015933
  2. Complement C3d. In: Wikidata. https://www.wikidata.org/wiki/Q76829529