Diseases

Complex Regional Pain Syndromes

Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

5 entry terms
  • CRPS (Complex Regional Pain Syndromes)
  • Complex Regional Pain Syndrome
  • Pain Syndromes, Regional Complex
  • Acute Regional Pain Syndrome
  • Chronic Regional Pain Syndrome

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • Reflex Sympathetic Dystrophy (1995-1999)

MeSH Hierarchy

Tree Numbers

  1. C10w.177.195w
  2. C10w.668w.829w.250w

MeSH Record

NLM Classification

WL 544

AMA Style

References

  1. National Library of Medicine. Complex Regional Pain Syndromes. Medical Subject Headings (MeSH). 2026. Unique ID D020918. http://id.nlm.nih.gov/mesh/2026/D020918
  2. Complex Regional Pain Syndromes. In: Wikipedia. https://en.wikipedia.org/wiki/Complex_regional_pain_syndrome
  3. Complex Regional Pain Syndromes. In: Wikidata. https://www.wikidata.org/wiki/Q1066311