Chemicals and Drugs

Connectin

A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

21 entry terms
  • M-Band Proteins
  • M-Line 185 kDa Protein
  • M-Protein (muscle)
  • Muscle M-Line Protein
  • Myomesin
  • Skelemins
  • Titin
  • Titin 1
  • Titin 2
  • Titin Kinase
  • alpha-Connectin
  • beta-Connectin
  • Kinase, Titin
  • M Band Proteins
  • M Line 185 kDa Protein
  • M-Line Protein, Muscle
  • Muscle M Line Protein
  • Protein, Muscle M-Line
  • Proteins, M-Band
  • alpha Connectin
  • beta Connectin

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Connectin. Medical Subject Headings (MeSH). 2026. Unique ID D064211. http://id.nlm.nih.gov/mesh/2026/D064211
  2. Connectin. In: Wikipedia. https://en.wikipedia.org/wiki/Titin
  3. Connectin. In: Wikidata. https://www.wikidata.org/wiki/Q74314