Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Coombs Test

A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

36 entry terms
  • Antiglobulin Consumption Test
  • Antiglobulin Test
  • Antihuman Globulin Consumption Test
  • Coombs' Test
  • Antiglobulin Consumption Tests
  • Antiglobulin Tests
  • Consumption Test, Antiglobulin
  • Consumption Tests, Antiglobulin
  • Coomb Test
  • Coomb's Test
  • Test, Antiglobulin
  • Test, Antiglobulin Consumption
  • Test, Coombs
  • Test, Coombs'
  • Tests, Antiglobulin
  • Tests, Antiglobulin Consumption
  • Anti-Human Globulin Consumption Test
  • Direct Antiglobulin Test
  • Direct Coombs Test
  • Indirect Antiglobulin Test
  • Indirect Coombs Test
  • Anti Human Globulin Consumption Test
  • Antiglobulin Test, Direct
  • Antiglobulin Test, Indirect
  • Antiglobulin Tests, Direct
  • Antiglobulin Tests, Indirect
  • Coombs Test, Direct
  • Coombs Test, Indirect
  • Direct Antiglobulin Tests
  • Indirect Antiglobulin Tests
  • Test, Direct Antiglobulin
  • Test, Direct Coombs
  • Test, Indirect Antiglobulin
  • Test, Indirect Coombs
  • Tests, Direct Antiglobulin
  • Tests, Indirect Antiglobulin

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

Indexing Annotation

for erythrocytes only: for lymphocytes consider HISTOCOMPATIBILITY TESTING or CYTOTOXICITY TESTS, IMMUNOLOGIC

MeSH Record

History Note

2013 (1966)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.812.735.050.375.150w
  2. E05.200.812.735.050.375.150w
  3. E05.478.594.760.050.375.150w

AMA Style

References

  1. National Library of Medicine. Coombs Test. Medical Subject Headings (MeSH). 2026. Unique ID D003298. http://id.nlm.nih.gov/mesh/2026/D003298
  2. Coombs Test. In: Wikipedia. https://en.wikipedia.org/wiki/Coombs_test
  3. Coombs Test. In: Wikidata. https://www.wikidata.org/wiki/Q740056