Structured Summary
Abstract
An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
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Classification
Broader headings
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MeSH Record
Synonyms
5 entry terms
- Coproporphyrinogen III Oxidases
- Coproporphyrinogenase
- III Oxidases, Coproporphyrinogen
- Oxidase, Coproporphyrinogen
- Oxidases, Coproporphyrinogen III
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
91(76); was see under OXIDOREDUCTASES 1976-90
MeSH Record
Previous Indexing
- Carboxy-Lyases (1972-1974)
- Coproporphyrins (1975)
- Oxidoreductases (1975)
- Porphyrins (1972-1974)
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AMA Style
References
- National Library of Medicine. Coproporphyrinogen Oxidase. Medical Subject Headings (MeSH). 2026. Unique ID D003304. http://id.nlm.nih.gov/mesh/2026/D003304
- Coproporphyrinogen Oxidase. In: Wikidata. https://www.wikidata.org/wiki/Q24768974