Chemicals and Drugs

Cortactin

A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).

MeSH Record

Classification

Broader headings

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MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1983)

MeSH Hierarchy

Tree Numbers

  1. D05.750w.078w.730.281
  2. D12.644w.360.024w.280
  3. D12.776w.157w.057w.014
  4. D12.776w.220.525.281
  5. D12.776w.476.024w.311
  6. D12.776w.744w.390

AMA Style

References

  1. National Library of Medicine. Cortactin. Medical Subject Headings (MeSH). 2026. Unique ID D051356. http://id.nlm.nih.gov/mesh/2026/D051356
  2. Cortactin. In: Wikidata. https://www.wikidata.org/wiki/Q24722941